Pathology: Hemodynamic

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0 [{"id":75165,"quiz_id":"5670","answer_id":null,"answerType_id":"0","created_at":"2016-05-31 10:39:31","updated_at":"2016-05-31 10:52:24","questionName":"A 25-year-old man experiences chest pain on exercise when he attempts to climb three flights of stairs. This pain is relieved by sublingual nitroglycerin. He is 178 cm tall and weighs 101 kg. His blood pressure is 130\/85 mm Hg. Laboratory studies show a total serum cholesterol of 550 mg\/dL with an HDL cholesterol component of 25 mg\/dL. The blood glucose is 120 mg\/dL. He is worried about these findings because his brother died of a myocardial infarction at age 34. Which of the following conditions is this man most likely to have?","questionTimeSeconds":"30","questionTimeMinutes":"1","questionImagePath":null,"position":0,"explanation":" The very high cholesterol with symptoms of coronary artery disease at such a young age, coupled with the family history, are all consistent with familial hypercholesterolemia. In most persons with hypercholessterolemia from multifactorial causes, includi","question_score_id":null,"lang":null,"questionAudioPath":null},{"id":75183,"quiz_id":"5670","answer_id":null,"answerType_id":"0","created_at":"2016-05-31 11:42:15","updated_at":"2016-05-31 11:42:15","questionName":"A 68-year-old woman has survived multiple episodes of pulmonary thromboembolism during the past three months. On physical examination there are no abnormal findings. Which of the following is the most likely underlying condition leading to this patient's recurrent pulmonary thromboembolism?","questionTimeSeconds":"30","questionTimeMinutes":"1","questionImagePath":null,"position":null,"explanation":"The recurrent episodes suggest a hypercoagulable state, and carcinomas can do this (Trousseau syndrome) by releasing substances that act as thromboplastins.","question_score_id":null,"lang":null,"questionAudioPath":null},{"id":75179,"quiz_id":"5670","answer_id":null,"answerType_id":"0","created_at":"2016-05-31 11:23:27","updated_at":"2016-05-31 11:23:27","questionName":"A 57-year-old man has had blood pressure measurements in the range of 160\/95 to 180\/110 mm Hg for many years. He has taken no medications. A renal scan reveals kidneys of normal size for age. These findings with benign nephrosclerosis are most likely to occur with which of the following vascular changes?","questionTimeSeconds":"30","questionTimeMinutes":"1","questionImagePath":null,"position":null,"explanation":"Hyaline arteriolosclerosis is a feature of long-standing hypertension and is part of benign nephrosclerosis which may go on for many years with no complications. The small arterioles are thickened with pink (hyaline) proteinaceous deposits.","question_score_id":null,"lang":null,"questionAudioPath":null},{"id":75166,"quiz_id":"5670","answer_id":null,"answerType_id":"0","created_at":"2016-05-31 10:46:59","updated_at":"2016-05-31 10:52:24","questionName":"In a clinical study of patients with diabetes mellitus, a group of patients is found who have had blood glucose measurements ranging from 140 to 180 mg\/dL for at least 10 years. Rectal biopsies from these patients now show that there is a form of osmotic cellular injury present in arterioles. This form of injury is most likely to be manifested elsewhere in the body by which of the following complications?","questionTimeSeconds":"30","questionTimeMinutes":"1","questionImagePath":null,"position":1,"explanation":"The hyperglycemia leads to formation of sorbitol in tissues not requiring insulin for glucose uptake, resulting in osmotic cellular injury. This can occur in small vessels, retina, kidney, and nerves. The failure of erection and ejaculation results from d","question_score_id":null,"lang":null,"questionAudioPath":null},{"id":75182,"quiz_id":"5670","answer_id":null,"answerType_id":"0","created_at":"2016-05-31 11:28:51","updated_at":"2016-05-31 11:28:51","questionName":"A 45-year-old man feels some crushing chest pain along with numbness in his left arm after shoveling 15 cm of snow off his driveway. Three hours later he collapses and is taken to the emergency room. Which of the following laboratory tests run on a blood specimen is most useful in this situation?","questionTimeSeconds":"30","questionTimeMinutes":"1","questionImagePath":null,"position":null,"explanation":"Elevations in CK enzyme are going to be seen acutely with myocardial infarction beginning within 3 hours and remaining for 3 days. The total CK reflects changes in any striated muscle, and is not specific for cardiac muscle. The CK-MB fraction is most spe","question_score_id":null,"lang":null,"questionAudioPath":null},{"id":75175,"quiz_id":"5670","answer_id":null,"answerType_id":"0","created_at":"2016-05-31 11:17:13","updated_at":"2016-05-31 11:17:13","questionName":"A study of pathologic findings in the islets of Langerhans is performed. It is observed that insulitis may occur in the islets. The inflammatory infiltrate is predominantly composed of T lymphocytes. Which of the following is most likely to occur as a consequence of insulitis?","questionTimeSeconds":"30","questionTimeMinutes":"1","questionImagePath":null,"position":null,"explanation":" An insulitis is seen with type I diabetes mellitus. Actually, it is rare to see it because by the time the patients present with overt diabetes mellitus, the islets are long gone.","question_score_id":null,"lang":null,"questionAudioPath":null}]
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A 25-year-old man experiences chest pain on exercise when he attempts to climb three flights of stairs. This pain is relieved by sublingual nitroglycerin. He is 178 cm tall and weighs 101 kg. His blood pressure is 130/85 mm Hg. Laboratory studies show a total serum cholesterol of 550 mg/dL with an HDL cholesterol component of 25 mg/dL. The blood glucose is 120 mg/dL. He is worried about these findings because his brother died of a myocardial infarction at age 34. Which of the following conditions is this man most likely to have?

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