Lasts for several months and can show no symptoms.
Lasts for a few days, but shows very few mild symptoms.
Lasts for several months with many severe symptoms.
Macrophages would engulf bacteria.
T helper cells are activated.
Bacteria would be destroyed on surface e.g. lysozyme and inflammation.
Anaerobic granulomas that contain dead bacteria and macrophages.
Aerobic granulomas that contain dead bacteria and macrophages.
Anaerobic granulomas that contain active bacteria and macrophages.
The resist being engulfed in phagocytosis.
They are engulfed in phagocytosis but resist the mechanisms of the digestive enzymes.
They are engulfed and destroyed in phagocytosis, but the bacterial DNA remains in the host cell.
The bacteria cause symptoms, but cannot be detected by doctors as they are inside the macrophages.
The macrophages prevent the bacteria from respiring and replicating, until the immune system is weakened and the infection becomes active.
The bacteria are dead inside the macrophages, so they do not cause any symptoms.
TB reduces number of B cells and therefore antibodies cannot be produced.
TB prevents T memory cells from being produced, so the response to secondary infection will be slow.
They suppress the T cells, reducing production of B cells and therefore antibodies, as well as reducing attack by T killer cells.
If the person's immune system is weakened when the bacteria are being held by macrophages.
If the person's immune system can't contain the disease when it first infects the lungs.
If the lungs become infected a second time.
Poor/cramped living conditions
Lack of vitamin C
Bacteria multiply and diffuse through surfaces to other cells.
Bacteria quickly multiply and destroy lung tissue, creating holes and cavities.
Bacteria quickly multiply and spread to all surrounding tissues.
Shortness of breath
Coughing (often blood)
Loss of appetite
Involuntary muscle contractions
Excessive desire to exercise
Fever and fatigue
Effectors act to warm body to new set point.
Sympathetic nervous system is activated by infection.
Neutrophils and macrophages release chemicals that raise the set point for core body temperature in hypothalamus.
Main symptom is swollen pineal gland.
Bacteria remains in the lungs and doesn't infect other parts.
Bacteria moves and infects other parts of body.
Main symptom is enlarged lymph gland.
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