Liver Pathology

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Put the steps of the metabolisation and excretion of bilirubin in order.

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Conjugated bilirubin is secreted out in bile and into the small intestine

Conjugated bilirubin is metabolised by gut microflora to form urobilinogen

Bilirubin is conjugated with glucuronide.

Haem is broken down. This process includes the removal of iron and its transport back to the spleen where it is reused in Haemopoiesis.

Bilirubin (unconjugated) is also formed from this process.

Product can be recirculated back to the liver and into the kidneys to be secreted in urine, or be further metabolised to form Stercobilonogen where it is then secreted out with faeces

Bound in albumin, Unconjugated bilirubin is transported to the liver where it is metabolise


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