UoM Immunology Lecture 1-5 (Year 2, Sem 2, 2017)

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Order the steps in which Immunoglobulin A takes to enter the gut.

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Is internalised

Dimerises into a dimer via a J-chain

IgA is transported out into the gut on its apical side

Receptor is cleaved and is left as a secretory component (also helps protect IgA from destruction)

Poly Ig receptor binds it


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