There are many methods in which adipose tissue can help in the storage and release of excess energy

fatty acid desposition require a lower amount if energy for breakdown

Metabolic problems associated with adipose tissue failure only occur in the fasted state when adipose tissue is actively releasing fatty acids

Abdomine is bloated

There is an increase of lipids in liver

An increase in serum concentration of protocollagen III peptide would be seen mainly at the fatty liver stage

Fibrosis is primarily due overproduction od the protein elastin by the fivroblasts eithin the lungs

Alveolar don’t present a significant relavance in respiration

Alceolar macrophages are effectively the second line defence

When alveolar macrophages ingest particles, they produce substances that can damage the epithelium

Don’t click this cant get rid of it

High exposure will be handles well by lungs, but loe exposure won’t

Being exposed to any level of exposure is harmful

In the case of relatively short-term exposure, it would appear that a low level of particles can be handled safely by the lungs, but a high level is potentially dangerous

The amount of glucose made is directly proportional the how much energy is present in her body

Metabolism of large volume of ethanol leads leads to depletion of NAD+ which is needed by one reaction in the beta-oxidation pathway as a hydrogen atom/electron acceptor, resulting in inhibition of the pathway.

Hydrogen tends to block the pathway if NADL chemicals and inhibts hormone production

It is unlikely that her collapse was purely the result of the level of alcohol in his blood

She would unable to mobilise his glycogen reserve due to the large amount of alcohol that she had consumed

Her ability to carry out glucogenisis would have been restricted due to the large amount of of alcohol she had consumed

Her blood glucose concentration was solely the results of not having eaten

When adipose tissue acumulates less energy will be formed

Some of the consequences of adipose tissue failure are the result of the tissue being overloaded whilst others are due to the equilibrium point being moved

adipose tissue failure only occurs when the tissue is substantially overloaded with fat

There is no evidence that eicosanoids play a significant rold in the inflammatory reponse to biologically reactive particles such as sillicates

All reactive particles play a role in cell death

Wheras it would appear that inert particles will only trigger macrophage responses such as the repirstory bursts when taken up by phagocytosis, more reactive particles may trigger these responses through other means such as interaction with cell plasma membrane

Irrespective if the nutritional state, fatty acids are are arriving at the liver at a faster rate than they can be handled by the beta-oxidation pathway

When a traicyglycerol is exposed to an infection it reacts quicker

In the fasted state, fatty acids are arriving at the liver at a faster rate than they can be handled by the beta-oxidation pathway

The level of sulphar dioxide exposure is strongly correlated with the level of ozone exposure

There had been a rapif increase in size of particles in recent years

It is difficult to determine whether sulphat dioxide has a specific impact on health

The average size of particles has decreased in the UK in recent years

Presence of lipid peroxidation products in serum and red blood cells

Very few fatty acid deposits present

No lipid perocidation products present in serum

Low levels of antioxidant vitamins such as vitamin C in the circulation

Whilst there is some correlation between asthma and sensitivity to the ozone, there is very significant individual variation

The ozone does not affect an individuls health in any way

The level of infection depends on that individuals ethnic background