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The CEP Quiz!

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What type of singalling: 2 cell signalling, close by, simple diffusion

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what type of signalling - self-regulating

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Ligand (first messenger) for RTK

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ACHONDROPLASIA (dwarfism)

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The mutation is in which gene?

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what type of receptor is this? (RTK)

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the mutation causes dimerisation in the abscence of what binding

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Classify nAChR

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GPCR has how many transmembrane helices (number answer)

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which subunit of GPCRs has an inherent GTPase activity?

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ORDER GPCR

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GPCR in resting state, GDP bound to alpha
alpha GTPase activity GTP--> GDP + Pi
alpha (mainly) acts on effector
receptor binds to GPCR
GDP exchanged for GTP on alpha
ligand activates receptor

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vibrio cholerae acts on

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Bordetella pertussis acts on

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Gq/11 - acts on PLC then PIP2 then DAG and InsP3. DAG...

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