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block

19755 – During the replication of DNA 

Select the correct answer(s).  

(0/0)

---

B. mutations arising in a non-coding region are clinically unimportant

C. deletion of a whole gene will always be detectable by karyotype analysis

E. RNA polymerase is important in the replication process 

D. point mutations may result in an abnormally short protein chain 

A. introns are spliced out of the DNA molecule

none

19126 – The polymerase chain reaction 

Select the correct answer(s).  

(0/0)

---

C. is an ideal quantitative test for the detection of amplified oncogenes

E. can be used to detect increased transcription of a normal gene 

D. cannot detect the presence of an organism after the patient is symptomatic

A. involves amplification of the target DNA using an RNA primer

B. is a very sensitive technique for the detection of HIV 

none

13986 – S:The possession of an X chromosome in excess of the normal complement is less harmful than the possession of an extra autosome because R:only one X chromosome in a cell is functional 

Select the correct answer(s).  

(0/0)

---

S is true, R is true but not a valid explanation of S

S is true and R is false

Both S and R are false 

S is false and R is true

S is true, R is true and a valid explanation of S 

none

10324 – What type of underlying genetic abnormality is most commonly seen with osteogenesis imperfecta 

Select the correct answer(s).  

(0/0)

---

C. Genomic imprinting

A. Point mutations

D. Deletions

B. Gonadal mosaicism 

E. Triplet repeat mutations 

none

25406 – Infection with human immunodeficiency virus (HIV) is characterised by 

Select the correct answer(s).  

(0/0)

---

D. circulating viral DNA in the peripheral blood

E. depressed serum immunoglobulin levels 

B. an early drop in CD8 positive T lymphocytes

A. an early acute viral infection 

C. a positive Mantoux test throughout the illness

none

10356 – What type of underlying genetic abnormality is most commonly seen with Fragile x syndrome 

Select the correct answer(s).  

(0/0)

---

A. Point mutations

E. Triplet repeat mutations 

C. Genomic imprinting

D. Deletions 

B. Gonadal mosaicism

none

10330 – What type of underlying genetic abnormality is most commonly seen with cystic fibrosis 

Select the correct answer(s).  

(0/0)

---

B. Gonadal mosaicism

E. Triplet repeat mutations 

C. Genomic imprinting

D. Deletions 

A. Point mutations

none

12536 – A young man is diagnosed as having red-green colour blindness. Of his relatives, the one LEAST likely to carry (or to manifest the effects of) the relevant gene is his 

Select the correct answer(s).  

(0/0)

---

A. father 

E. daughter 

D. maternal grandmother

B. mother

C. maternal grandfather

none

10342 – What type of underlying genetic abnormality is most commonly seen with beta-thalassaemia 

Select the correct answer(s).  

(0/0)

---

E. Triplet repeat mutations 

D. Deletions

A. Point mutations 

B. Gonadal mosaicism

C. Genomic imprinting

none

16974 – S:The effects of carcinogenic initiators on DNA chemistry are reversible because R:tumours do not eventuate if the subsequent promoter application is delayed. 

Select the correct answer(s).  

(0/0)

---

S is true, R is true and a valid explanation of S

Both S and R are false 

S is true and R is false

S is false and R is true 

S is true, R is true but not a valid explanation of S

none

18820 – The most usual chromosome complement in Klinefelter's syndrome is 

Select the correct answer(s).  

(0/0)

---

A. 44 autosomes plus XXY 

B. 44 autosomes plus XY

C. 45 autosomes plus XXY

E. 43 autosomes plus XXY 

D. 44 autosomes plus XO

none

10336 – What type of underlying genetic abnormality is most commonly seen with Angelman syndrome 

Select the correct answer(s).  

(0/0)

---

B. Gonadal mosaicism

E. Triplet repeat mutations 

A. Point mutations

D. Deletions

C. Genomic imprinting 

none

15248 – Hyperacute rejection of renal grafts is typically due to 

Select the correct answer(s).  

(0/0)

---

E. delayed type hypersensitivity 

C. humoral antibodies 

A. cytotoxic T cells

D. blood borne infection

B. immunological enhancement

none

19426 – In the case of a woman who is heterozygous for a recessive X-linked disorder 

Select the correct answer(s).  

(0/0)

---

C. the disorder may be partially expressed 

D. all of her sons will be affected

E. Barr bodies will not be detectable 

B. the diagnosis can be made by chromosomal banding studies

A. the abnormal allele is preferentially inactivated in her cells

none

13427 – S:Among the immunoglobulins only IgA and IgM characteristically include J chains because R:J chains are found in those immunoglobulins which exist in the monomeric form 

Select the correct answer(s).  

(0/0)

---

S is true and R is false 

S is true, R is true but not a valid explanation of S 

S is false and R is true

Both S and R are false

S is true, R is true and a valid explanation of S