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Cancer

mitosis-4

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Which gene is defective in cancers?

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Explanation

The tumour suppressor genes regulate cell cycle and create checkpoints. It is defective within cancer patients therefore allows malfunctioning cells to replicate without being checked. The proto-ocogenes also become abnormally active meaning cell division is too rapid.

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What is cancer?

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Match the the cancer stages to their explanation

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Stage 1
Stage 2
Stage 3

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Promotion - growth of tumour
Progression - tumour spreads
Initiation - induction of a mutation in a critical cell

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4 characteristics of a BENIGN tumour

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4 characteristics of a MALIGNANT tumour

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4 risk factors of cancer

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There are 6 phases in Mitosis Cell division. They are:

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Match the phases to the explanation.

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Prophase
Prometaphase
Metaphase
Anaphase
Telophase
Cytokinesis

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Mitotic spindles attach to kinetochores.
Chromotids separate in to daughter chromosomes and more to opposite poles.
Two daughter cells emerge by proteins in the middle splitting in to two.
Chromosomes arrive at opposite poles and nuclear envelope material surrounds them.
Chromosomes condense and become visible. Spidle fibre emerge from centrosomes. Nuclear envelope begins to break down.
Chromosomes align with centrosomes. Each sister chromatid is attached to a spindle fibre.

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