Medicine - Liver

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Question 1 of 1

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347677

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Which clotting factors are vitamin K dependent?

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Which of these would indicate hepatocellular damage rather than cholestasis?

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Explanation

ALT (alanine aminotransferase) and AST (aspartate aminotransferase) are located in the cytoplasm of hepatocytes. Large increases in aminotransferases favour hepatocellular damage - this pattern of LFT abnormality is known as 'hepatic'. Both aminotransfera

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Which LFT abnormality would indicate a 'cholestatic' or 'obstructive' picture?

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Explanation

ALP is present in lots of tissues, but within the liver it is located in cell membranes of hepatic sinusoids and biliary canaliculi, so levels are elevated in with intra and extrahepatic biliary obstruction, and sinusoidal obstruction. GGT is also found a

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Significantly raised levels of ______ suggest haemochromatosis.

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Explanation

Haemochromatosis is a genetic condition that causes too much iron to be absorbed from the diet. Excess iron is stored in various organs, but mainly the liver. Treatment is regular removal of blood. If treatment is started early before complications, outlo

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Which of these clotting factors is prothrombin?

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What is Vitamin B12?

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Explanation

Cobalamin = Vitamin B12. Thiamine = Vitamin B1. Riboflavin = Vitamin B2. Folate = Vitamin B9.

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Prothrombin time (PT) is prolonged in liver disease. Which of the following is true:

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Explanation

All clotting factors are produced in the liver, including vitamin K dependent ones (which includes prothrombin (factor II)). Vitamin K dependent coagulation factors have short half-lives (5-72hrs) so PT changes can occur relatively quickly following liver

Medicine - Liver

Question 1 of 1

Time Left

Which clotting factors are vitamin K dependent?

Select the correct answer(s).

(0/0)

Which of these would indicate hepatocellular damage rather than cholestasis?

Select the correct answer(s).

(0/0)

Explanation

Which LFT abnormality would indicate a 'cholestatic' or 'obstructive' picture?

Select the correct answer(s).

(0/0)

Explanation

Significantly raised levels of ______ suggest haemochromatosis.

Fill in the blanks

(0/0)

Explanation

Which of these clotting factors is prothrombin?

Select the correct answer(s).

(0/0)

What is Vitamin B12?

Select the correct answer(s).

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Explanation

Prothrombin time (PT) is prolonged in liver disease. Which of the following is true:

Select the correct answer(s).

(0/0)

Explanation

Thrombocytopenia is a low blood ________ count.

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