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[{"id":547341,"quiz_id":"26581","answer_id":null,"answerType_id":"0","created_at":"2018-08-26 07:23:47","updated_at":"2018-08-26 07:23:47","questionName":"En relaci\u00f3n a las mol\u00e9culas del CMH de clase I cl\u00e1sicas \u00bfLa cadena beta 2 microglobulina no es polim\u00f3rfica?","questionTimeSeconds":"0","questionTimeMinutes":"1","questionImagePath":"uploads\/inmuno-preguntas-seminario-3\/1.7.jpg","position":null,"explanation":"La cadena alfa es polimorfica, presentado el mayor polimorfis, alfa 1. Pero la cadena B2-microglobulina NO es polim\u00f3rfica. Es com\u00fan para todos los seres humanos","question_score_id":null,"lang":"","questionAudioPath":null},{"id":547343,"quiz_id":"26581","answer_id":null,"answerType_id":"0","created_at":"2018-08-26 07:25:52","updated_at":"2018-08-26 07:25:52","questionName":"En relaci\u00f3n a las mol\u00e9culas del CMH de clase I cl\u00e1sicas \u00bfEl surco que alberga el p\u00e9ptido antig\u00e9nico involucra dominios que pertenecen solo a la cadena alfa?","questionTimeSeconds":"0","questionTimeMinutes":"1","questionImagePath":"uploads\/inmuno-preguntas-seminario-3\/1.8.jpg","position":null,"explanation":"El surco que alberga el p\u00e9ptido antig\u00e9nico involucra dominios que pertenecen solo a la cadena alfa. El surco est\u00e1 formado por las subunidades alfa1 y alfa2","question_score_id":null,"lang":"","questionAudioPath":null},{"id":548105,"quiz_id":"26581","answer_id":null,"answerType_id":"0","created_at":"2018-08-27 12:20:21","updated_at":"2018-08-27 12:20:21","questionName":"\u00bfEn cuanto a la expresi\u00f3n de las mol\u00e9culas de clase II del CMH, una cadena alfa de origen materno puede expresarse junto a una cadena beta de origen paterno?\r\n","questionTimeSeconds":"0","questionTimeMinutes":"1","questionImagePath":"uploads\/inmuno-preguntas-seminario-3\/9.3.jpg","position":null,"explanation":"Exite codominacia y multialelismo del sistema de CMH-II. Por lo que ambos alelos correspondientes para las cedenas alfa y beta se expresan y adem\u00e1s, una cadena alfa de origen materno puede expresarse junto a una cadena beta de origen paterno y viceversa. A esto se llama TRANSASOCIACI\u00d3N","question_score_id":null,"lang":"","questionAudioPath":null},{"id":547845,"quiz_id":"26581","answer_id":null,"answerType_id":"0","created_at":"2018-08-27 12:11:59","updated_at":"2018-08-27 12:11:59","questionName":"\u00bfEn relaci\u00f3n al CMH, el concepto de polimorfismo refiere a la existencia de m\u00faltiples genes?","questionTimeSeconds":"0","questionTimeMinutes":"1","questionImagePath":"uploads\/inmuno-preguntas-seminario-3\/9.1.jpg","position":null,"explanation":"En relaci\u00f3n al CMH, el concepto de polimorfismo refiere a la existencia de m\u00faltiples ALELOS","question_score_id":null,"lang":"","questionAudioPath":null},{"id":548114,"quiz_id":"26581","answer_id":null,"answerType_id":"0","created_at":"2018-08-27 12:39:54","updated_at":"2018-08-27 12:39:54","questionName":"\u00bfLas mol\u00e9culas del CMH de clases I y II comparten, como propiedad estructural, la presencia de una cadena alfa con elevado polimorfismo?","questionTimeSeconds":"0","questionTimeMinutes":"1","questionImagePath":"uploads\/inmuno-preguntas-seminario-3\/10.1.jpg","position":null,"explanation":"","question_score_id":null,"lang":"","questionAudioPath":null},{"id":547344,"quiz_id":"26581","answer_id":null,"answerType_id":"0","created_at":"2018-08-26 07:36:39","updated_at":"2018-08-27 07:51:17","questionName":"En relaci\u00f3n a las mol\u00e9culas del CMH de clase I cl\u00e1sicas \u00bfLa enorme variabilidad que muestran las mol\u00e9culas del CMH de clase I se genera durante la ontogenia?","questionTimeSeconds":"0","questionTimeMinutes":"1","questionImagePath":null,"position":null,"explanation":"Se produce por 2 morivos:\r\n1) mediante mutaciones puntuales no durante la ontogenia, sino durante la MEIOSIS (GAMETAS)\r\n2) Proceso de conversi\u00f3n g\u00e9nica. Es un proceso de intercambio gen\u00e9tico y ocurre durante meiosis, en la reparaci\u00f3n de errores de apareamiento entre las bases del heterod\u00faplex de ADN\r\n","question_score_id":null,"lang":"","questionAudioPath":null},{"id":548107,"quiz_id":"26581","answer_id":null,"answerType_id":"0","created_at":"2018-08-27 12:22:57","updated_at":"2018-08-27 12:22:57","questionName":"\u00bfLos linfocitos B2 pueden reconocer p\u00e9ptidos antig\u00e9nicos presentados por mol\u00e9culas del CMH?","questionTimeSeconds":"0","questionTimeMinutes":"1","questionImagePath":null,"position":null,"explanation":"","question_score_id":null,"lang":"","questionAudioPath":null},{"id":547337,"quiz_id":"26581","answer_id":null,"answerType_id":"0","created_at":"2018-08-26 06:56:35","updated_at":"2018-08-26 06:56:35","questionName":"En relaci\u00f3n a las mol\u00e9culas del CMH de clase I cl\u00e1sicas \u00bfLas mol\u00e9culas de clase I cl\u00e1sicas est\u00e1n integradas por 4 cadenas?","questionTimeSeconds":"0","questionTimeMinutes":"1","questionImagePath":"uploads\/inmuno-preguntas-seminario-3\/1.5.jpg","position":null,"explanation":"Est\u00e1 integradas por 2 cadenas (alfat y beta). Y cuatro dominios (alfa1,alfa2,alfa3 y beta2-microglobulina)","question_score_id":null,"lang":"","questionAudioPath":null},{"id":548110,"quiz_id":"26581","answer_id":null,"answerType_id":"0","created_at":"2018-08-27 12:28:19","updated_at":"2018-08-27 12:28:19","questionName":"\u00bfLos glicosaminoglicanos unen a las quimiocinas en la superficie luminal del endotelio?","questionTimeSeconds":"0","questionTimeMinutes":"1","questionImagePath":"uploads\/inmuno-preguntas-seminario-3\/9.6.jpg","position":null,"explanation":"","question_score_id":null,"lang":"","questionAudioPath":null},{"id":547346,"quiz_id":"26581","answer_id":null,"answerType_id":"0","created_at":"2018-08-26 07:43:29","updated_at":"2018-08-26 07:43:29","questionName":"En relaci\u00f3n a las mol\u00e9culas del CMH de clase II \u00bfEn un individuo, todos sus macr\u00f3fagos expresan las mol\u00e9culas DP, DQ y DR?","questionTimeSeconds":"0","questionTimeMinutes":"1","questionImagePath":null,"position":null,"explanation":"En un individuo, todos sus macr\u00f3fagos expresan las mol\u00e9culas DP, DQ y DR. Estas mol\u00e9culas tambi\u00e9n estan presentes en las CD y L.B. C\u00e9lulas presentadoras de ant\u00edgeno profesionales (CPAP)","question_score_id":null,"lang":"","questionAudioPath":null},{"id":547338,"quiz_id":"26581","answer_id":null,"answerType_id":"0","created_at":"2018-08-26 07:07:07","updated_at":"2018-08-26 07:07:07","questionName":"En relaci\u00f3n a las mol\u00e9culas del CMH de clase I cl\u00e1sicas \u00bfSe entiende por polimorfismo la capacidad de un individuo de expresar m\u00faltiples alelos para cada uno de sus genes cl\u00e1sicos del CMH?","questionTimeSeconds":"0","questionTimeMinutes":"1","questionImagePath":"uploads\/inmuno-preguntas-seminario-3\/1.6.jpg","position":null,"explanation":"Se entiende por polimorfismo la capacidad de UNA POBLACI\u00d3N de expresar m\u00faltiples alelos para cada uno de sus genes cl\u00e1sicos del CMH.\r\n\r\nEl polimorfismo gen\u00e9tico hace referencia a la existencia en una poblaci\u00f3n de m\u00faltiples alelos de un gen. Es decir, un polimorfismo es una variaci\u00f3n en la secuencia de un lugar determinado del ADN en los cromosomas (locus) entre los individuos de una poblaci\u00f3n.","question_score_id":null,"lang":"","questionAudioPath":null},{"id":548113,"quiz_id":"26581","answer_id":null,"answerType_id":"0","created_at":"2018-08-27 12:32:23","updated_at":"2018-08-27 12:32:23","questionName":"\u00bfLa maduraci\u00f3n de los endosomas involucra un incremento en su contenido en enzimas lisosomales y la disminuci\u00f3n de su pH interno?","questionTimeSeconds":"0","questionTimeMinutes":"1","questionImagePath":null,"position":null,"explanation":"","question_score_id":null,"lang":"","questionAudioPath":null},{"id":547336,"quiz_id":"26581","answer_id":null,"answerType_id":"0","created_at":"2018-08-26 06:49:30","updated_at":"2018-08-26 06:49:30","questionName":"En relaci\u00f3n a las mol\u00e9culas del CMH de clase I cl\u00e1sicas \u00bfCada mol\u00e9cula del CMH de clase I cl\u00e1sica es capaz de reconocer un \u00fanico p\u00e9ptido?","questionTimeSeconds":"0","questionTimeMinutes":"1","questionImagePath":"uploads\/inmuno-preguntas-seminario-3\/1.4.jpg","position":null,"explanation":"Cada mol\u00e9cula del CMH de clase I cl\u00e1sica es capaz de reconocer VARIOS p\u00e9ptido, PERO S\u00d3LO ES CAPAZ DE UNIRLOS, UNO POR VEZ.","question_score_id":null,"lang":"","questionAudioPath":null},{"id":547345,"quiz_id":"26581","answer_id":null,"answerType_id":"0","created_at":"2018-08-26 07:40:07","updated_at":"2018-08-26 07:40:07","questionName":"En relaci\u00f3n a las mol\u00e9culas del CMH de clase I cl\u00e1sicas \u00bfLas mol\u00e9culas de clase I cl\u00e1sicas unen el p\u00e9ptido antig\u00e9nico en el citosol?","questionTimeSeconds":"0","questionTimeMinutes":"1","questionImagePath":"uploads\/inmuno-preguntas-seminario-3\/1.10.jpg","position":null,"explanation":"Las mol\u00e9culas de clase I cl\u00e1sicas unen el p\u00e9ptido antig\u00e9nico en el RER.","question_score_id":null,"lang":"","questionAudioPath":null},{"id":548108,"quiz_id":"26581","answer_id":null,"answerType_id":"0","created_at":"2018-08-27 12:25:20","updated_at":"2018-09-04 15:40:11","questionName":"\u00bfLa autofagia permite la presentaci\u00f3n de ant\u00edgenos presentes en el citosol a trav\u00e9s de mol\u00e9culas de clase I del CMH?","questionTimeSeconds":"0","questionTimeMinutes":"1","questionImagePath":"uploads\/inmuno-preguntas-seminario-3\/semi3_025.jpg","position":null,"explanation":"La autofagia permite la presentaci\u00f3n de ant\u00edgenos presentes en el citosol a trav\u00e9s de mol\u00e9culas de CLASE II del CMH","question_score_id":null,"lang":"","questionAudioPath":null}]