Immunology Quiz 2

immunology-quiz-2

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A 32- year old, blood type A positive male receives a kidney transplant from a blood type B positive female donor with whom he had a 6-antigen HLA match. Once the kidney is anastomosed to the man’s vasculature, the transplant team immediately beings to observe swelling and interstitial hemorrhage. After the surgery, the patient developed fever and leukocytosis and produced no urine. Which of the following is the most likely answer?

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Tissue grafts placed in some sites in the body do not elicit immune responses. The grafts do not induce graft rejection via "host-versus-graft" or "graft-versus-host" mechanisms. Such locations are termed "immunologically privileged sites," and they include what regions?

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Allergic contact dermatitis is one of the most common dermatologic conditions and is the result of contact with an external agent. These reactions can be seen anywhere on the body, and symptoms include localized erythema, vesicles, scale, and pruritus. Members of the Rhus family, including poison ivy, poison oak, and poison sumac, cause this type of allergic reaction. Allergic contact dermatitis is an example of

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IgE is mostly found fixed in the tissues on mast cells that bear receptors for it, as well as on circulating basophils and activated eosinophils. The ligation of cell-bound IgE by antigens such as pollen or mold triggers activation of these cells at the site of antigen entry into the tissues. The release of inflammatory lipid mediators, cytokines, and chemokines at sites of IgE-triggered reactions results in the recruitment of eosinophils and basophils to augment what response?

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What is the difference between hyperacute rejection, acute rejection, and chronic rejection?

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The HLA-DP, HLA-DR, HLA-DQ, and HLA-DP code for

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Many bacteria are recognized, ingested, and destroyed by immune cells, and these bacteria are not pathogenic in normal individuals. Bacterial pathogens, however, often have polysaccharide capsules that allow them to resist direct engulfment by these immune cells. These bacteria become susceptible to destruction when they are coated with an antibody that engages the Fc receptors on immune cells, triggering the uptake and destruction of the bacteria. Coating a microorganism with molecules that allow its destruction by immune cells is known as what?

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An exaggerated immune response which is harmful to the host is termed a hypersensitivity reaction. Different individuals are sensitive to different antigens. First contact with the antigen usually does not elicit a hypersensitivity reaction, but only 'sensitizes' the individual. Subsequent exposure elicits the allergic response. In case of type I hypersensitivity the reactions are mediated by which of the following?

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While playing in the woods with friends, a 14-year-old African-American male is bitten by an insect. Minutes later he notices swelling and redness at the site of the insect bite. Which substance has directly led to the wheal formation?

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A 5-year-old female suffers from recurrent infections by Aspergillus species, Pseudomonas species, and Staphylococcus aureus. The patient's neutrophils are examined in the laboratory and they fail to react during the nitroblue tetrazolium test. Which of the following is most likely dysfunctional in this patient?

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A 32-year-old pregnant woman (para 2) presents to the clinic for a routine ultrasound. The fetus has become anemic and levels of unconjugated bilirubin have increased dramatically. Which type of hypersensitivity reaction has occurred and what is mediating the disease state?

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A 7-year-old boy presents to your office with facial eczema. He has a history of multiple, recurrent infections, including multiple episodes of pneumonia that lasted several weeks and otitis media. Laboratory measurements of serum immunoglobulins showed increased IgE and IgA but decreased IgM. Which of the following additional abnormalities would you expect to observe in this patient?

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A 30-year-old Caucasian male presents with hemoptysis and uremia. Blood tests show the presence of anti-basement membrane antibodies specific for collagen located in glomerular and pulmonary basement membranes. The patient undergoes plasmaphoresis to help reduce the amount of anti-basement membrane antibodies. Which of the following diseases is of the same hypersensitivity category as this disease?

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While hunting, a 45-year-old Caucasian male is stung by a bee. He begins to feel unwell and is taken to the hospital. Upon arrival, it is noted that the patient is hypotensive with a blood pressure of 60/40 mmHg. Furthermore, the patient is tachycardic and edematous. What is responsible for this patient's presentation?

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75684

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While hunting, a 45-year-old Caucasian male is stung by a bee. He begins to feel unwell and is taken to the hospital. Upon arrival, it is noted that the patient is hypotensive with a blood pressure of 60/40 mmHg. Furthermore, the patient is tachycardic and edematous. What is responsible for this patient's presentation?

Immunology Quiz 2

Question 1 of 1

Time Left

Select the correct answer(s).

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Tissue grafts placed in some sites in the body do not elicit immune responses. The grafts do not induce graft rejection via "host-versus-graft" or "graft-versus-host" mechanisms. Such locations are termed "immunologically privileged sites," and they include what regions?

Select the correct answer(s).

(0/0)

Select the correct answer(s).

(0/0)

Select the correct answer(s).

(0/0)

What is the difference between hyperacute rejection, acute rejection, and chronic rejection?

Select the correct answer(s).

(0/0)

The HLA-DP, HLA-DR, HLA-DQ, and HLA-DP code for

Select the correct answer(s).

(0/0)

Select the correct answer(s).

(0/0)

Select the correct answer(s).

(0/0)

While playing in the woods with friends, a 14-year-old African-American male is bitten by an insect. Minutes later he notices swelling and redness at the site of the insect bite. Which substance has directly led to the wheal formation?

Select the correct answer(s).

(0/0)

Select the correct answer(s).

(0/0)

A 32-year-old pregnant woman (para 2) presents to the clinic for a routine ultrasound. The fetus has become anemic and levels of unconjugated bilirubin have increased dramatically. Which type of hypersensitivity reaction has occurred and what is mediating the disease state?

Select the correct answer(s).

(0/0)

Select the correct answer(s).

(0/0)

Select the correct answer(s).

(0/0)

Select the correct answer(s).

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Select the correct answer(s).

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