Immunology

immunology-6

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Question 1 of 1

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214996

120

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Match the following Immunogloblins

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Match the text
IgG
IgA
IgM
IgD
IgE

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Dominant in serum. Activates the classical pahtway in the complement system. Contains 2 heavy gamma chains.
Delta chains, not much is known about the function of this Ig. Monomeric
Found in high amounts in allergic responses (Type I)
Found in the mothers milk after birth and is also associated with mucous membranes. Dimeric but is also polymeric.
Largest Ab in the immune system. Involved in ABO antigen repsonses w/ blood cells.

214997

120

none

Which cells are effectors of the adaptive immune system

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214998

120

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Which of the following are Granulocytes?

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214999

120

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Which receptors are involved in the recognition of microbial conserved molecular patterns in the innate immune system?

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215000

420

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Match the following defintions

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Antigenicity
Immunogenicty
Eptiope
Haptens
MHC Class I
MHC Class II
MHC Class III

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The portion of a molecule that is recognised and bound by a Ab (also TCR/MHC molecules). AKA the antigenic determinant region.
Secreted proteins that have immune functions such as the complement system or inflamatory molecules
Found on all nucleated cells
A molecule that is capable of producing/stimulating an immune response
Small molecules that are incapable of producing an immune response when administered on their own but can when administered with another product. Once the response has been produced they are capable of reacting with the products of the response.
Found on immune cells - used for Antigen presenting
A soluble molecule that is capable of binding to specific antibodies has this property

215001

120

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What factors influence immunogenicty?

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215002

240

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What mechanisms do Adjuvants use to enhance the immune response to an antigen?

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215003

120

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Types of Adjuvants

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Complete Freunds Adjuvant
Incomplete Freunds Adjuvant
Aluminium Salt Adjuvants

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Most frequently used as adjuvants for vaccine delivery and best used with strongly immunogenic antigens. It can result in mild inflammatory reactions.
Contains paraffin oil, killed mycobacteria and monoosletate
Often used in booster injections as it does not produce significantly severe reactions.

215004

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What ligand on a T Cell binds with B7 on B Cells/APCs?

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215005

120

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Postulates of the Clonal Selection Theory

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Each lymphocyte bears a single type of

of a unique specificity.

Interaction between a foreign molecule and a lymphocyte receptor that is capable of

to it with a high

results in lymphocyte activation.

The differentiated effectors cells derived from an activated lymphocyte will bear receptors of

specificity to the parental cell.

215006

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What cytokines are produced by Th1 cells?

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215007

240

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Macth the following molecules with their properties

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Match the text
T Cell Receptors
CD3
CD8
CD4
CD2

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Recognises the Ag-MHC II complex. Only able to bind small peptodes.
Found on cytotoxic T cells - co-receptor.
Found on T helper cells - co-receptor.
Signal Transduction
Cell adhesion molecule

215008

300

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T Cell Dependent B Cell Activation

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Match the Text
1
2
3
4
5
6
7

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The antigen is interalised and processed.
Th cell recognises the Ag-MHC II complex via the TCR binding to it which provides signal 1 for the T Cell.
T cell activation eads to upregulation of CD40L which binds to CD40 on the B cell
The activated T cell produces IL-2 and the activated B cell produces specific antibodies.
B7 binds to CD28 on the T cell
The antigen binds to the BCR, providing signal 1 to the B cell
Antigenic peptide is displayed on an MHC Class II molecule.

215009

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What type of molecules are present in T cell independent activation of B cells?

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Immunology

Question 1 of 1

Time Left

Match the following Immunogloblins

Match the text (click and drag)

(0/0)

IgG

IgA

IgM

IgD

IgE

Dominant in serum. Activates the classical pahtway in the complement system. Contains 2 heavy gamma chains.

Delta chains, not much is known about the function of this Ig. Monomeric

Found in high amounts in allergic responses (Type I)

Found in the mothers milk after birth and is also associated with mucous membranes. Dimeric but is also polymeric.

Largest Ab in the immune system. Involved in ABO antigen repsonses w/ blood cells.

Which cells are effectors of the adaptive immune system

Select the correct answer(s).

(0/0)

Which of the following are Granulocytes?

Select the correct answer(s).

(0/0)

Which receptors are involved in the recognition of microbial conserved molecular patterns in the innate immune system?

Select the correct answer(s).

(0/0)

Match the following defintions

Match the text (click and drag)

(0/0)

Antigenicity

Immunogenicty

Eptiope

Haptens

MHC Class I

MHC Class II

MHC Class III

The portion of a molecule that is recognised and bound by a Ab (also TCR/MHC molecules). AKA the antigenic determinant region.

Secreted proteins that have immune functions such as the complement system or inflamatory molecules

Found on all nucleated cells

A molecule that is capable of producing/stimulating an immune response

Small molecules that are incapable of producing an immune response when administered on their own but can when administered with another product. Once the response has been produced they are capable of reacting with the products of the response.

Found on immune cells - used for Antigen presenting

A soluble molecule that is capable of binding to specific antibodies has this property

What factors influence immunogenicty?

Select the correct answer(s).

(0/0)

What mechanisms do Adjuvants use to enhance the immune response to an antigen?

Select the correct answer(s).

(0/0)

Types of Adjuvants

Match the text (click and drag)

(0/0)

Complete Freunds Adjuvant

Incomplete Freunds Adjuvant

Aluminium Salt Adjuvants

Most frequently used as adjuvants for vaccine delivery and best used with strongly immunogenic antigens. It can result in mild inflammatory reactions.

Contains paraffin oil, killed mycobacteria and monoosletate

Often used in booster injections as it does not produce significantly severe reactions.

What ligand on a T Cell binds with B7 on B Cells/APCs?

Select the correct answer(s).

(0/0)

Postulates of the Clonal Selection Theory

Fill in the blanks

(0/0)

What cytokines are produced by Th1 cells?

Select the correct answer(s).

(0/0)

Macth the following molecules with their properties

Match the text (click and drag)

(0/0)

T Cell Receptors

CD3

CD8

CD4

CD2

Recognises the Ag-MHC II complex. Only able to bind small peptodes.

Found on cytotoxic T cells - co-receptor.

Found on T helper cells - co-receptor.

Signal Transduction

Cell adhesion molecule

T Cell Dependent B Cell Activation