DNA MCQ - DNA Damage

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0 [{"id":129905,"quiz_id":"8667","answer_id":null,"answerType_id":"3","created_at":"2016-11-24 20:01:37","updated_at":"2016-11-27 12:29:03","questionName":"Put the 6-4PP dimers in order of abundance, starting with the most abundant. ","questionTimeSeconds":"0","questionTimeMinutes":"2","questionImagePath":null,"position":10,"explanation":"","question_score_id":null,"lang":null,"questionAudioPath":null},{"id":129906,"quiz_id":"8667","answer_id":null,"answerType_id":"0","created_at":"2016-11-24 20:03:23","updated_at":"2016-11-27 12:29:03","questionName":"How many degrees is the bend in the DNA strand caused by 6-4PPs?","questionTimeSeconds":"0","questionTimeMinutes":"2","questionImagePath":null,"position":11,"explanation":"6-4PPs cause a DNA bend of 44 degree whilst CPDs cause a bend of 7-9 degrees.","question_score_id":null,"lang":null,"questionAudioPath":null},{"id":130294,"quiz_id":"8667","answer_id":null,"answerType_id":"0","created_at":"2016-11-26 18:02:35","updated_at":"2016-11-27 12:29:03","questionName":"What wavelength of longwave UV light does photoactivation of Photosensitizing furocoumarins or furanocoumarins occur?","questionTimeSeconds":"0","questionTimeMinutes":"2","questionImagePath":null,"position":9,"explanation":"At this wavelengths psoralens are able to form covalent adducts to pyrimidine bases on the DNA strand leading to crosslinks, distortion and unwinding. This process is aided by the planar structure of the molecules which allows it to slip in between base p","question_score_id":null,"lang":null,"questionAudioPath":null},{"id":129769,"quiz_id":"8667","answer_id":null,"answerType_id":"2","created_at":"2016-11-24 10:21:24","updated_at":"2016-11-27 12:29:03","questionName":"Match the amino acid with it's resulting molecule following the process of deamination (spontaneous removal of an amine group) in hydrolytic pH in a temperature dependent reaction.","questionTimeSeconds":"0","questionTimeMinutes":"2","questionImagePath":"uploads\/dna-damage\/Deamination.png","position":1,"explanation":"","question_score_id":null,"lang":null,"questionAudioPath":null},{"id":129816,"quiz_id":"8667","answer_id":null,"answerType_id":"0","created_at":"2016-11-24 12:20:03","updated_at":"2016-11-27 12:29:03","questionName":"Oxidative DNA damage involves what species of atom(s)\/molecule(s)\/complex(s)?","questionTimeSeconds":"0","questionTimeMinutes":"2","questionImagePath":null,"position":5,"explanation":"Singlet oxygen, hydrogen peroxide, superoxide anion radicals and Fenton reaction-generated hydroxyl radicals are all types of ROS involved in oxidative damage to DNA. They interact with other molecules and convert them into radicals, perpetuating the chai","question_score_id":null,"lang":null,"questionAudioPath":null},{"id":130289,"quiz_id":"8667","answer_id":null,"answerType_id":"0","created_at":"2016-11-26 14:51:54","updated_at":"2016-11-27 12:29:03","questionName":"What type of DNA damage can IR cause?","questionTimeSeconds":"0","questionTimeMinutes":"2","questionImagePath":null,"position":13,"explanation":"Consiering that IR damage is primarily caused by radicals, understandably it causes similar types of damage to that of oxidative damage. In particular, if these radical species occur in similar DNA regions multiple closely spaced sections of DNA can be da","question_score_id":null,"lang":null,"questionAudioPath":null},{"id":130290,"quiz_id":"8667","answer_id":null,"answerType_id":"0","created_at":"2016-11-26 15:00:24","updated_at":"2016-11-27 12:29:03","questionName":"Which of these forms of chemical carcinogens can be used in chemotherapy?","questionTimeSeconds":"0","questionTimeMinutes":"2","questionImagePath":null,"position":14,"explanation":"Alkylating agents can inhibit cell division in tumour cells by adding alkyl groups to guanine bases in DNA helices thus crosslinking them which goes on to prevent the unwinding of DNA in replication.","question_score_id":null,"lang":null,"questionAudioPath":null},{"id":129904,"quiz_id":"8667","answer_id":null,"answerType_id":"1","created_at":"2016-11-24 20:00:33","updated_at":"2016-11-27 12:29:03","questionName":"Fill in the blanks","questionTimeSeconds":"0","questionTimeMinutes":"2","questionImagePath":null,"position":8,"explanation":"","question_score_id":null,"lang":null,"questionAudioPath":null},{"id":130288,"quiz_id":"8667","answer_id":null,"answerType_id":"0","created_at":"2016-11-26 14:48:54","updated_at":"2016-11-27 12:29:03","questionName":"What is the main form of DNA damage that Ionising Radiation causes?","questionTimeSeconds":"0","questionTimeMinutes":"2","questionImagePath":null,"position":12,"explanation":"About 80% of damage caused by IR is due to water radiolysis via ROS and other radical species with 65% of this damage being due to hydroxyl radicals alone.","question_score_id":null,"lang":null,"questionAudioPath":null},{"id":129817,"quiz_id":"8667","answer_id":null,"answerType_id":"0","created_at":"2016-11-24 12:22:59","updated_at":"2016-11-27 12:29:03","questionName":"Radical Oxidative Species can be generated in the cell from...","questionTimeSeconds":"0","questionTimeMinutes":"2","questionImagePath":"uploads\/dna-damage\/ROS.png","position":6,"explanation":"","question_score_id":null,"lang":null,"questionAudioPath":null},{"id":129767,"quiz_id":"8667","answer_id":null,"answerType_id":"1","created_at":"2016-11-24 10:09:58","updated_at":"2016-11-27 12:29:03","questionName":"Fill in the blanks","questionTimeSeconds":"0","questionTimeMinutes":"2","questionImagePath":"uploads\/dna-damage\/Tautomeric shift.png","position":0,"explanation":"","question_score_id":null,"lang":null,"questionAudioPath":null},{"id":129823,"quiz_id":"8667","answer_id":null,"answerType_id":"1","created_at":"2016-11-24 12:37:43","updated_at":"2016-11-27 12:29:03","questionName":"Fill in the blanks","questionTimeSeconds":"0","questionTimeMinutes":"2","questionImagePath":"uploads\/dna-damage\/CPDs and 6-4PPs.png","position":7,"explanation":"","question_score_id":null,"lang":null,"questionAudioPath":null},{"id":129813,"quiz_id":"8667","answer_id":null,"answerType_id":"0","created_at":"2016-11-24 12:07:14","updated_at":"2016-11-27 12:29:03","questionName":"What is depurination\/depyrimidination?","questionTimeSeconds":"0","questionTimeMinutes":"2","questionImagePath":null,"position":2,"explanation":"Base loss occurs when N-glycosidic bond is hydrolysed via H2O protonation which in turn leads to abasic sites.","question_score_id":null,"lang":null,"questionAudioPath":null},{"id":129815,"quiz_id":"8667","answer_id":null,"answerType_id":"0","created_at":"2016-11-24 12:11:06","updated_at":"2016-11-27 12:29:03","questionName":"What is the rate of Pyrimidine to Purine loss?","questionTimeSeconds":"0","questionTimeMinutes":"2","questionImagePath":null,"position":4,"explanation":"","question_score_id":null,"lang":null,"questionAudioPath":null},{"id":129814,"quiz_id":"8667","answer_id":null,"answerType_id":"0","created_at":"2016-11-24 12:09:19","updated_at":"2016-11-27 12:29:03","questionName":"Which amino acid depyrimidinates\/depurinates 1.5 times as slowly in alkaline conditions?","questionTimeSeconds":"0","questionTimeMinutes":"2","questionImagePath":null,"position":3,"explanation":"","question_score_id":null,"lang":null,"questionAudioPath":null}]
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Put the 6-4PP dimers in order of abundance, starting with the most abundant.

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