Diabetes Drugs

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Match the different diabetes drug classes to their mode of action

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Metformin

Sulfonylureas (SU)

Meglitinides

Acarbose

Glitazones

DPP-4 Inhibitors (gliptins)

Glucagon- like polupetitde-1 agonists

Sodium glucose co-transporter inhibitors (SLGT2 inhibitor)

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Bind to a receptor on the surface of beta cells in the pancreas, stimulating the release of insulin lowering blood sugar

Acts on receptors in the nucleus of the fat, liver and muscle cells, causing changes with enhance the action of insulin on these cells

Acts on liver, inhibiting hepatic glucose production, and 2. Increases insulin-mediated peripheral glucose uptake

Increase insulin secretion, suppress glucagon secretion and slow gastric emptying

Inhibit the enzyme DPP-4

Alpha glucosidase inhibitor acting on the enzyme that breads down complex carbs in food in the intestine into simple sugars (glucose), slowing down absorption and reducing blood glucose peak following a meal

Lower blood glucose by blocking a protein in the kidneys that is responsible for the reabsorption of glucose into the bloodstream, thereby increase the excretion of glucose in the urine

Stimulate insulin release from the beta cells in the pancreas but from a different receptor site to SU


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