Chapter 068 : Pharmacologic Management of Lower Urinary Tract Storage and Emptying Failure

chapter-068-pharmacologic-management-of-lower-urinary-tract-storage-and-emptying-failure

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Question 1 of 1

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The effects of administration of antimuscarinic agent to an individual with an overactive bladder (OAB) include all EXCEPT:

Select the correct answer(s).

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Which of the following muscarinic receptor subtypes is the most common in human detrusor smooth muscle?

Select the correct answer(s).

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Which of the following muscarinic receptor subtypes is predominantly responsible for the mediation of bladder contraction in human detrusor smooth muscle?

Select the correct answer(s).

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The use of antimuscarinic agents to treat OAB is limited by their lack of uroselectivity. Which of the following is not a recognized side effect of antimuscarinic agents?

Select the correct answer(s).

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Which of the following characteristics increases the possibility for an antimuscarinic agent to pass the bloodbrain barrier? (Multiple answers are possible.)

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As a therapeutic antimuscarinic agent, propantheline bromide is:

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Oxybutynin exerts its clinical effects on the urinary bladder primarily by:

Select the correct answer(s).

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The Committee on Pharmacologic Treatment of the Fourth (2008) International Consultation on Incontinence assessed agents according to the Oxford Guidelines, according to level of evidence and grade of recommendation with respect to treatment of detrusor overactivity (DO). Which of the following (multiple answers are possible) did not receive a level of evidence rating of 1 and a grade of recommendation of A?

Select the correct answer(s).

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The pharmacologic characteristics of which class of drugs would suggest that they may be active during the filling/ storage phase of micturition and effective in abolishing DO, yet with no effect on normal bladder contraction?

Select the correct answer(s).

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Which of the following pharmacologic actions is most probably responsible for the effects of oxybutynin when given systemically?

Select the correct answer(s).

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Which two of the following muscarinic receptor subtypes are not known to be involved in the potential antimuscarinic side effects of dry mouth, constipation, tachycardia, drowsiness, and blurred vision?

Select the correct answer(s).

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The primary adverse event reported with the usage of oxybutynin-transdermal has been:

Select the correct answer(s).

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Which of the following agents is relatively selective for M3 receptor blockade?

Select the correct answer(s).

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Which of the following drugs have a theoretical advantage for causing less cognitive dysfunction and why? (Multiple answers are possible.)

Select the correct answer(s).

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Chapter 068 : Pharmacologic Management of Lower Urinary Tract Storage and Emptying Failure

Question 1 of 1

Time Left

The effects of administration of antimuscarinic agent to an individual with an overactive bladder (OAB) include all EXCEPT:

Select the correct answer(s).

(0/0)

Which of the following muscarinic receptor subtypes is the most common in human detrusor smooth muscle?

Select the correct answer(s).

(0/0)

Which of the following muscarinic receptor subtypes is predominantly responsible for the mediation of bladder contraction in human detrusor smooth muscle?

Select the correct answer(s).

(0/0)

The use of antimuscarinic agents to treat OAB is limited by their lack of uroselectivity. Which of the following is not a recognized side effect of antimuscarinic agents?

Select the correct answer(s).

(0/0)

Which of the following characteristics increases the possibility for an antimuscarinic agent to pass the bloodbrain barrier? (Multiple answers are possible.)

Select the correct answer(s).

(0/0)

As a therapeutic antimuscarinic agent, propantheline bromide is:

Select the correct answer(s).

(0/0)

Oxybutynin exerts its clinical effects on the urinary bladder primarily by:

Select the correct answer(s).

(0/0)

Select the correct answer(s).

(0/0)

The pharmacologic characteristics of which class of drugs would suggest that they may be active during the filling/ storage phase of micturition and effective in abolishing DO, yet with no effect on normal bladder contraction?

Select the correct answer(s).

(0/0)

Which of the following pharmacologic actions is most probably responsible for the effects of oxybutynin when given systemically?

Select the correct answer(s).

(0/0)

Which two of the following muscarinic receptor subtypes are not known to be involved in the potential antimuscarinic side effects of dry mouth, constipation, tachycardia, drowsiness, and blurred vision?

Select the correct answer(s).

(0/0)

The primary adverse event reported with the usage of oxybutynin-transdermal has been:

Select the correct answer(s).

(0/0)

Which of the following agents is relatively selective for M3 receptor blockade?

Select the correct answer(s).

(0/0)

Which of the following drugs have a theoretical advantage for causing less cognitive dysfunction and why? (Multiple answers are possible.)

Select the correct answer(s).

(0/0)

Of the following agents, which is actively excreted by the kidney in the proximal convoluted tubules?

Select the correct answer(s).

(0/0)

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