Biol113

biol113

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Give 3 diseases that occur from deletions

Cri-du-Chat(5p minus), Prader-Willi(15q1.12 paternally derived), Angelman(15q1.12 maternally derived)

Explanation

Cri-du-chat: cat like cry, wide face, retardation. Prada-Willi: obesity, poor sexual development. Angelman: Happy demeanour, speech problems, retardation

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213249

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t(14;21) is the translocation that causes what syndrome?

Familial Down's

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{"id":994276,"question_id":"213249","created_at":"2017-05-31 10:21:37","updated_at":"2017-05-31 10:21:37","answerTitle":"Familial Down's","isAnswerCorrect":"1","isAnswerBlank":null,"isInSecondMatchingColumn":null,"sequenceOrder":null,"lang":null,"type":0}

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213251

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What is the name of the translocated chromosome found in chronic myelocytic leukaemia

Philadelphia chromosome

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{"id":994281,"question_id":"213251","created_at":"2017-05-31 10:22:46","updated_at":"2017-05-31 10:22:46","answerTitle":"Philadelphia chromosome","isAnswerCorrect":"1","isAnswerBlank":null,"isInSecondMatchingColumn":null,"sequenceOrder":null,"lang":null,"type":0}

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213263

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What chemical properties suggest the 'transforming principle' is not a protein?

Resistant to proteases

Explanation

Principle is DNA, positive reaction to the Dische test

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{"id":994329,"question_id":"213263","created_at":"2017-05-31 11:04:01","updated_at":"2017-05-31 11:04:01","answerTitle":"Resistant to proteases ","isAnswerCorrect":"1","isAnswerBlank":null,"isInSecondMatchingColumn":null,"sequenceOrder":null,"lang":null,"type":0}

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213264

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Who conducted an experiment using bacteriophages to determine DNA is injected into cells?

Hershey and Chase

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{"id":994330,"question_id":"213264","created_at":"2017-05-31 11:05:28","updated_at":"2017-05-31 11:05:28","answerTitle":"Hershey and Chase","isAnswerCorrect":"1","isAnswerBlank":null,"isInSecondMatchingColumn":null,"sequenceOrder":null,"lang":null,"type":0}

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213265

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What ensure specific base pairing and how many are present in each pair?

Hydrogen bonding, 2 between A-T and 3 between G-C

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{"id":994331,"question_id":"213265","created_at":"2017-05-31 11:07:53","updated_at":"2017-05-31 11:07:53","answerTitle":"Hydrogen bonding, 2 between A-T and 3 between G-C","isAnswerCorrect":"1","isAnswerBlank":null,"isInSecondMatchingColumn":null,"sequenceOrder":null,"lang":null,"type":0}

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213266

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What is the type of replication where each strand of DNA acts as a template for the other?

Semi-conservative replication

Explanation

Demonstrated in the Meselson-Stahl experiment

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{"id":994332,"question_id":"213266","created_at":"2017-05-31 11:09:09","updated_at":"2017-05-31 11:09:09","answerTitle":"Semi-conservative replication","isAnswerCorrect":"1","isAnswerBlank":null,"isInSecondMatchingColumn":null,"sequenceOrder":null,"lang":null,"type":0}

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213267

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Give 4 things needed for DNA strand synthesis

DNA polymerase, Single-stranded template DNA, All 4 dNTPs, Free 3' hydroxyl primers

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{"id":994333,"question_id":"213267","created_at":"2017-05-31 11:10:46","updated_at":"2017-05-31 11:10:46","answerTitle":"DNA polymerase, Single-stranded template DNA, All 4 dNTPs, Free 3' hydroxyl primers","isAnswerCorrect":"1","isAnswerBlank":null,"isInSecondMatchingColumn":null,"sequenceOrder":null,"lang":null,"type":0}

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213268

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What 2 types of strand are found at each replication fork?

Leading and Lagging

Explanation

Replication begins at the origin, only done in the 5' to 3' direction, Lagging strand synthesised discontinuously

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{"id":994334,"question_id":"213268","created_at":"2017-05-31 11:12:38","updated_at":"2017-05-31 11:12:38","answerTitle":"Leading and Lagging","isAnswerCorrect":"1","isAnswerBlank":null,"isInSecondMatchingColumn":null,"sequenceOrder":null,"lang":null,"type":0}

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213269

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What enzyme fills in gaps between Okazaki fragments and which seals these gaps?

DNA polymerase 1, DNA ligase

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{"id":994335,"question_id":"213269","created_at":"2017-05-31 11:13:44","updated_at":"2017-05-31 11:13:44","answerTitle":"DNA polymerase 1, DNA ligase","isAnswerCorrect":"1","isAnswerBlank":null,"isInSecondMatchingColumn":null,"sequenceOrder":null,"lang":null,"type":0}

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213270

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What are auxotrophs?

Mutant strains that can't synthesis a particular molecule required for growth

Explanation

Only grow in that molecules presence, can screen to find out what

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{"id":994336,"question_id":"213270","created_at":"2017-05-31 11:15:54","updated_at":"2017-05-31 11:15:54","answerTitle":"Mutant strains that can't synthesis a particular molecule required for growth","isAnswerCorrect":"1","isAnswerBlank":null,"isInSecondMatchingColumn":null,"sequenceOrder":null,"lang":null,"type":0}

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213271

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What is the One Gene- One Enzyme Hypothesis?

Each enzyme in a pathway is encoded for by a gene

Explanation

Not all gene products are enzymes- 'One Gene- One Polypeptide'

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{"id":994337,"question_id":"213271","created_at":"2017-05-31 11:17:16","updated_at":"2017-05-31 11:17:16","answerTitle":"Each enzyme in a pathway is encoded for by a gene","isAnswerCorrect":"1","isAnswerBlank":null,"isInSecondMatchingColumn":null,"sequenceOrder":null,"lang":null,"type":0}

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213272

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What is the messenger that transfers information from the nucleus to the cytoplasm?

RNA

Explanation

RNA is transcribed from DNA and translated into protein

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{"id":994338,"question_id":"213272","created_at":"2017-05-31 11:19:14","updated_at":"2017-05-31 11:19:14","answerTitle":"RNA","isAnswerCorrect":"1","isAnswerBlank":null,"isInSecondMatchingColumn":null,"sequenceOrder":null,"lang":null,"type":0}

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213273

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3 bases that code for a protein are called what?

A codon

Explanation

Specific, Redundant and almost Universal

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{"id":994339,"question_id":"213273","created_at":"2017-05-31 11:22:41","updated_at":"2017-05-31 11:22:41","answerTitle":"A codon","isAnswerCorrect":"1","isAnswerBlank":null,"isInSecondMatchingColumn":null,"sequenceOrder":null,"lang":null,"type":0}

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213275

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What is the adapter that links mRNA and amino acids?

tRNAs

Explanation

80 nucleotides long, single stranded, folded into a clover leaf shape

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{"id":994344,"question_id":"213275","created_at":"2017-05-31 11:28:41","updated_at":"2017-05-31 11:28:41","answerTitle":"tRNAs","isAnswerCorrect":"1","isAnswerBlank":null,"isInSecondMatchingColumn":null,"sequenceOrder":null,"lang":null,"type":0}

Biol113

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