Aspirin

Dextrose 50%

Tylenol

Adrenaline

Platelet inhibitor, anti-inflammatory

Adsorbent

Antiemetic

Analgesic, antipyretic

Binds with hemoglobin to help biodegrade cyanide

Not precisely known, but evidence is that it acts to depress hyper stimulated labyrinthine functions or associated neural pathways. It is also thought to inhibit cholinergic stimulation in the vestibular and associated neural pathways.

Reduces production of thromboxane which mediates platelet aggregation.

Binds and adsorbs ingested toxins from the gastrointestinal tract

Pyrexic child, severe sepsis or septic shock

Acute cyanide poisoning with impaired LOC

Chest pain, cardiac in origin

Relief of nausea and vomiting, can be associated with motion sickness and nausea vomiting associated with Meniere’s Disease, or medication induced N/V particularly Narcotics.

Hypersensitivity, hyperglycemia

Hypersensitivity, acetaminophen-induced liver disease

Hypersensitivity to ASA or other NSAIDs, active peptic ulcers

Hypersensitivity to dimenhydrinate or tartrazine.

Patients with cardiac history, pregnancy

Potentially fatal hepatotoxicity can result from overdose Patients with liver disease, are malnourished, are chronic alcoholics or are taking medications that induce hepatic enzymes are at greater risk for acetaminophen hepatotoxicity

Do not administer to patient with decreased LOC. If ipecac has been administered, wait 10 minutes.

Asthma patient

Tachycardia, palpitations, headache, anxiety, arrhythmias, nausea/ vomiting

Heartburn, nausea/ vomiting, wheezing, prolonged bleeding

Tachycardia, nausea/vomiting, hypertension

nausea/ vomiting, cramping may be seen in overdose in children and nothing noted in adults till liver function deterioration

IV

PO/PR

PO, chewed

PO

Adult: 325-650 mg every 4-6 hours, not to exceed 4000 mg/24 hours, Pediatric: 10-15 mg/kg every 4-6 hours, not to exceed 5 doses in 24 hours

160 – 325 mg

Adult: 25 g, may be repeated as necessary Pediatric: 2 – 4 mL/kg of D25W concentration

12 years and older: 1 mg with repeat in 15 min as needed Under 12 years: 0.1 mg/kg to a max of 1 mg with repeat in 15 min as needed

Onset: Immediate Peak effects: Varies Duration: Varies based on gastrointestinal function, will act until excreted

Onset: 1 min Peak effects: 30 min Duration: 1 - 2 hours

Onset: Immediate (IV), 20-30 minutes (IM) Peak effects: Varies Duration: 3-6 hours

Onset: Within 20 min Peak effects: Varies Duration: 2 – 3 hours

81 mg and 325 mg tablets

50 mg/ml

1 mg/mL (requires reconstitution)

Oral – Immediate release tablet (325 mg, 500 mg), caplet (325 mg, 500 mg), extended release caplet (650 mg), gel cap (500 mg), chewable tablet (80 mg, 160 mg), rapidly- dissolving tablet (80 mg , 160 mg), suspension (80 mg/mL, 32 mg/mL) Rectal – Suppository (120 mg, 160 mg, 325 mg, 650 mg)

Always ensure that a blood glucose reading is obtained before administration

Only services that respond to industries where cyanide exposure can occur will stock drug

Administer regardless whether patient has taken their daily ASA dose

Retraining and certification is required by a physician every 2 years