0 [{"id":140266,"quiz_id":"9058","answer_id":null,"answerType_id":"0","created_at":"2016-12-11 00:31:42","updated_at":"2016-12-11 00:34:59","questionName":"A 76-year-old dialysis-dependent woman with a history of multiple prior abdominal operations presents to the emergency room with worsening abdominal pain. Workup raises your suspicions for ischemic bowel. She last underwent hemodialysis 3 days prior, and is currently uremic. How will you best prepare the patient for emergent celiotomy?","questionTimeSeconds":"0","questionTimeMinutes":"20","questionImagePath":null,"position":0,"explanation":"The patient has chronic renal failure (CRF), which results in a coagulopathy that must be corrected prior to surgery. The mechanism leading to the coagulopathy associated with CRF is thought to be due to uremic inactivation of von Willebrand Factor (vWF).","question_score_id":null,"lang":null,"questionAudioPath":null},{"id":140278,"quiz_id":"9058","answer_id":null,"answerType_id":"0","created_at":"2016-12-11 00:40:01","updated_at":"2016-12-11 00:40:01","questionName":"A 39-year-old male is referred to your clinic for treatment of a cecal mass diagnosed by surveillance colonoscopy. His father, paternal grandmother, and paternal uncle all developed colon cancer by their fifth decade. Mutation of which of the following genes is associated with this man's disease?","questionTimeSeconds":"0","questionTimeMinutes":"20","questionImagePath":null,"position":null,"explanation":"Hereditary nonpolyposis colorectal cancer (HNPCC), also known as Lynch syndrome, is an autosomal dominant hereditable disease caused by mutations in DNA mismatch repair genes including hMSH2, hMLH1, hPMS1, and hPMS2. Polyps are smaller than those seen in ","question_score_id":null,"lang":null,"questionAudioPath":null}]

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A 76-year-old dialysis-dependent woman with a history of multiple prior abdominal operations presents to the emergency room with worsening abdominal pain. Workup raises your suspicions for ischemic bowel. She last underwent hemodialysis 3 days prior, and is currently uremic. How will you best prepare the patient for emergent celiotomy?

Select the correct answer(s).  

(0/0)

Explanation

The patient has chronic renal failure (CRF), which results in a coagulopathy that must be corrected prior to surgery. The mechanism leading to the coagulopathy associated with CRF is thought to be due to uremic inactivation of von Willebrand Factor (vWF).

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Transfuse the patient with packed red blood cells (PRBC)

Administer conjugated estrogens

Arrange for dialysis

Administer cryoprecipitate

Administer desmopressin

none

A 39-year-old male is referred to your clinic for treatment of a cecal mass diagnosed by surveillance colonoscopy. His father, paternal grandmother, and paternal uncle all developed colon cancer by their fifth decade. Mutation of which of the following genes is associated with this man's disease?

Select the correct answer(s).  

(0/0)

Explanation

Hereditary nonpolyposis colorectal cancer (HNPCC), also known as Lynch syndrome, is an autosomal dominant hereditable disease caused by mutations in DNA mismatch repair genes including hMSH2, hMLH1, hPMS1, and hPMS2. Polyps are smaller than those seen in

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BRCA1

BRCA2

APC

K-Ras

hMSH2