Pharmacotherapeutics 1 - 2 (Drug receptor interactions)

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Affinity

Agonist

Antagonist

Occupancy

Efficacy

Potency

Specificity

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The measure of how well a drug can bind (Measured by Kd)

The measure of an agonists ability to produce a desired response/therapeutic effect (activate receptors)

The proportion of receptors occupied by the drug

A drug that binds to a receptor and produces a response

A drug that binds to a receptor without producing a response (blocks or dampens the agonists response)

An index of how much drug is required to administer to produce a desired response

The interaction of the drug with a specific structure/receptor


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