c. 35%

e. 5%

a. 70%

d. 90%

b. 20%

d. Learning disability is evident before the age of 1 year

b. It is due to trisomy of chromosome 21

a. It is the most common genetic cause of learning disability

c. Children with Down syndrome have characteristic facies and habitus

e. IQ in adults is usually less than 50

c. Children with Down syndrome have characteristic facies and habitus

Children with the syndrome may have rocker-bottom feet

It is due to trisomy of chromosome 17

It is caused only by non-disjunction of chromosomes during meiosis

Children with the syndrome have normal genitalia

IQ is usually normal

The usual genetic cause is a Robertsonian translocation

Raised IgM and IgG levels are features

Most children with Down syndrome are born to mothers under the age of 35

Incidence per 1000 live births increases for women over 35

About half of people with Down syndrome have congenital heart defects

German measles

Measles

Syphilis

Hypothyroidism

Diabetes

Macrocephaly

Hypermetropia

Vascular dementia

Depression

Hyperthyroidism

Simian crease

Short stature

Kayser–Fleischer ring

Protruding tongue

High-arched palate

Klinefelter syndrome

Trisomy X

Down syndrome

XYY male

Turner syndrome

Obesity

Hypogenitalism

Acromicria

Mild to moderate learning disability

Tall stature

Paroxysms of crying

Epilepsy

Macrocephaly

Normal IQ

Micrognathia

Absence of a mental illness

Onset before age 12 years

IQ below 60

Onset before age 18 years

Deficit in at least one area of adaptive functioning