Cell and Molecular

cell-and-molecular

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Soalan 1 of 1

Waktu Kiri

24999

120

block

How are the 5' and 3' carbons linked in the sugar phosphate back bone?

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25000

120

none

'supercoiled DNA moves faster than relaxed DNA' True or False?

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(0/0)

25002

120

none

'DNA is unwound for transcription' True or False?

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(0/0)

25003

120

none

'DNA is unwound for cell division' True or False?

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(0/0)

25004

120

none

Select the best definition for Tm

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(0/0)

25005

120

none

what factor affects the Tm

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(0/0)

25006

120

none

at which temperature does annealing occur?

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(0/0)

25007

120

none

Order the steps of Initiation (Translation)

Padankan teks (klik dan seret)

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Padankan Teks
1
2
3
4

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Association of larger subunit. irreversible GTP hydrolysis mediates association of large s.u. to the small s.u. by action of elF5, this becomes the P site.
Formation of initiation complex (cap binding of mRNA to 43s)
Formation of 43s pre-initiation complex, 40S-elF3 bound by elF1A to a ternary complex of tRNA
Positioning at start codon: initiation complex unwinds mRNA using elF4 helicase, stops at start site AUG. recognition allows irreversible GTP hydrolysis of elF2 preventing further unwinding.

25009

240

none

order the steps of Elongation (translation)

Padankan teks (klik dan seret)

(0/0)

Padankan Teks
1
2
3
4

Klik dan seret
transpeptidation: c terminal of poly-peptide is uncoupled from Psite tRNA and bond is transferred to a.a. on A site (catalysed by peptidyl transferase)
GTP hydrolysis of EF1a induces conformational change in ribosome
aatRNA binds to A site on ribosome by base pairing with a codon
transloaction: GTP hydrolysis of EF2 causes 2nd conformational change Psite tRNA to be transferred to E site

25013

120

none

what enzyme catalyses the transfer of the bond from Psite tRNA to the neighbouring a.a on Asite tRNA?

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(0/0)

25014

120

none

order the steps of Termination (DNA replication)

Padankan teks (klik dan seret)

(0/0)

Padankan Teks
1
2
3
4

Klik dan seret
Release factors (eRFs) recognise and bind to stop codons inducing peptidly transferase to transfer peptidyl group to water instead of aatRNA
Inactive ribosomes release mRNA
uncharged tRNA is released from ribosome
Ribosome returns to two separate sub units

25016

240

none

match the following texts

Padankan teks (klik dan seret)

(0/0)

Padankan teks itu
Protein folding
covalent modifications
Proteolytic cleavage
Ribosomes
Large and small subunits

Klik dan seret
found on R.E.R, made of rRNA and ribosomal proteins
addition of side groups, dictate activity, life span or location
activates some inactive precursors (e.g. capsizes, zymogens)
combine only in the presence of mRNA and a 'charged' tRNA
protein is golden and mediated by molecular chaperones (e.g. Hsp70) or chaperonins

25017

360

none

Adapter hypothesis:

Isi tempat kosong

(0/0)

tRNA acts as a '

' linking amino acids to uncles acids. tRNAs align to form a

chain. the 3 base

allows base-pairing with corresponding

codon. the tRNA needs to be 'charged' this is done by

where the correct tRNA is selected for that mRNA sequence. the enzyme which catalyses this process is calle

the ribosome will then recognise and select the correct tRNA due to identifiers present on the

step and

loop.

25019

120

none

Match the following rules of DNA replication with their descriptions.

Padankan teks (klik dan seret)

(0/0)

Padankan teks itu
Semi-Conservative replication
starts at 'Origin'
can be uni/bidirectional
RNA primers require

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specific DNA sequence. prokaryotes have a single origin, eukaryotes have multiple.
(meselson-stahl experiment) leading strand synthesises continuously whilst the lagging strand synthesises discontinuously (Okazaki fragments). this means synthesis can always take place in the 5'-3' direction.
replication forks move in the same or opposite directions but it is always 5'-3' (leading and lagging strands just switch over depending on direction)
primers anneal to DNA strand allowing DNA polymerase to attach and synthesise new RNA strand and Okazaki fragments (semi-discontinuous)

25020

120

none

Cell and Molecular

Soalan 1 of 1

Waktu Kiri

How are the 5' and 3' carbons linked in the sugar phosphate back bone?

Pilih Jawapan yang Betul

(0/0)

'supercoiled DNA moves faster than relaxed DNA' True or False?

Pilih Jawapan yang Betul

(0/0)

'DNA is unwound for transcription' True or False?

Pilih Jawapan yang Betul

(0/0)

'DNA is unwound for cell division' True or False?

Pilih Jawapan yang Betul

(0/0)

Select the best definition for Tm

Pilih Jawapan yang Betul

(0/0)

what factor affects the Tm

Pilih Jawapan yang Betul

(0/0)

at which temperature does annealing occur?

Pilih Jawapan yang Betul

(0/0)

Order the steps of Initiation (Translation)

Padankan teks (klik dan seret)

(0/0)

1

2

3

4

Association of larger subunit. irreversible GTP hydrolysis mediates association of large s.u. to the small s.u. by action of elF5, this becomes the P site.

Formation of initiation complex (cap binding of mRNA to 43s)

Formation of 43s pre-initiation complex, 40S-elF3 bound by elF1A to a ternary complex of tRNA

Positioning at start codon: initiation complex unwinds mRNA using elF4 helicase, stops at start site AUG. recognition allows irreversible GTP hydrolysis of elF2 preventing further unwinding.

order the steps of Elongation (translation)

Padankan teks (klik dan seret)

(0/0)

1

2

3

4

transpeptidation: c terminal of poly-peptide is uncoupled from Psite tRNA and bond is transferred to a.a. on A site (catalysed by peptidyl transferase)

GTP hydrolysis of EF1a induces conformational change in ribosome

aatRNA binds to A site on ribosome by base pairing with a codon

transloaction: GTP hydrolysis of EF2 causes 2nd conformational change Psite tRNA to be transferred to E site

what enzyme catalyses the transfer of the bond from Psite tRNA to the neighbouring a.a on Asite tRNA?

Pilih Jawapan yang Betul

(0/0)

order the steps of Termination (DNA replication)

Padankan teks (klik dan seret)

(0/0)

1

2

3

4

Release factors (eRFs) recognise and bind to stop codons inducing peptidly transferase to transfer peptidyl group to water instead of aatRNA

Inactive ribosomes release mRNA

uncharged tRNA is released from ribosome

Ribosome returns to two separate sub units

match the following texts

Padankan teks (klik dan seret)

(0/0)

Protein folding

covalent modifications

Proteolytic cleavage

Ribosomes

Large and small subunits

found on R.E.R, made of rRNA and ribosomal proteins

addition of side groups, dictate activity, life span or location

activates some inactive precursors (e.g. capsizes, zymogens)

combine only in the presence of mRNA and a 'charged' tRNA

protein is golden and mediated by molecular chaperones (e.g. Hsp70) or chaperonins

Adapter hypothesis:

Isi tempat kosong

(0/0)

Match the following rules of DNA replication with their descriptions.

Padankan teks (klik dan seret)

(0/0)

Semi-Conservative replication