MI (transmural), cardiac surgery, Viral infections (coxackie B most common)

MI, Cardiac surgery, Viral Infections, Malignancy, Uraemia (renal failure), Bacterial infections (secondary to lung infection e.g. TB), Rheumatic fever,

Hypertrophic (obstructive), Dilated (congestive), Restrictive

Hypertrophy of LV wall causing outflow obstruction

defective myocardial contractility leading to atrophy & ventricular dilatation & cardiac failure

Abnormal rigidity of myocardium restricts filling and contraction

Most - unknown, few - Autosomal Dominant

Most - unknown, Some postviral myocarditis

Most - unknown, some - Infiltration by amyloid

Lesions seen in Rheumatic myocarditis - a central ill-defined area of degenerate material surrounded by a mixture of inflammatory leucocytes

Interstitial connective tissue of myocardium - usually near vessels, in subpericardial fibrous tissue and subendocardial connective tissue.

A cell usually found in Aschoff bodies. It is a large modified histiocyte. It has an irregular ribbon-like nucleus and extensive eosinophilic cytoplasm.

Aschoff body - Rheumatic Fever

Anitschow Myocyte - Rheumatic Fever

Organisation and fibrous scarring of affected valves ---> thickening and distortion of valve leaflets + chordae tendinae --> renders affected valves stenotic/incompetent