Local Anaesthetic

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416371
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LA agents

Cocokkan teks (klik dan seret)   

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Cocokkan teks

Lidocaine

Mepivacaine

Prilocaine

Articaine

Klik dan seret

most effective dental anaesthetic, onset: 5 mins, duration: 45 mins pulpal and 2-3 hrs soft tissue

More rapidly metabolised than lidocaine, half life 20 mins, increased soft and hard tissue diffusion, mainly metabolised in plasma good for liver compromised pts. good if prolonged tx and repeated LA required to avoid toxicity. onset: 5 mins, duration: 1-3 hours. shorter working time compared to lidocaine

similar to lidocaine, produces less vasodilation than lidocaine, useful if lidocaine inhibited, plain solution good if epinephrine CI, onset: 5 mins, duration: 45 mins pulpal, 2-3 hrs soft tissue

Felypressin doesn't work as well as epinephrine, weaker vasodilator than lidocaine, plain solution ideal if vasoconstrictor CI, CI with pregnancy as can pass across placenta causing metheamoglobinemia (cyanosis). felypressin can bring on labour, rapidly metabolised in liver good for pts with compromised liver function. onset: 2 mins, duration: 30 mins - 1hr.


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